%0 Figure %A Zhang, Weijia %A Duy Le, Thuc %A Liu, Lin %A Zhou, Zhi-Hua %A Li, Jiuyong %D 2016 %T An illustration of how the prior knowledge helping the causal structure construction. %U https://plos.figshare.com/articles/figure/An_illustration_of_how_the_prior_knowledge_helping_the_causal_structure_construction_/3170557 %R 10.1371/journal.pone.0152860.g003 %2 https://plos.figshare.com/ndownloader/files/4935910 %K miRNA regulation mechanisms %K Integrating Gene Regulatory Knowledge %K understanding cancer mechanisms %K target messenger RNAs %K framework %K performance increases monotonically %K BRCA %K miRNA target prediction %K miRNA targets %K Transcription Factor %K miRNA functions %K Expression Profiles Motivation microRNAs %K breast cancer %K C ausal m i RNA target D iscovery %K EMT %K modeling process %K E xpression profile %K gene expression data %K Computational methods %K gene regulation knowledge %K TF %K CIDER %K simulation study %X

Solid/dashed black lines indicate the edges correctly/incorrectly detected during the causal structure construction without the prior knowledge; Dotted brown lines indicate the edges added based on prior knowledge.

%I PLOS ONE