10.1371/journal.pone.0035787.g003
Fiona L. Wilkinson
Fiona
L. Wilkinson
Rebecca J. Holley
Rebecca
J. Holley
Kia J. Langford-Smith
Kia
J. Langford-Smith
Soumya Badrinath
Soumya
Badrinath
Aiyin Liao
Aiyin
Liao
Alex Langford-Smith
Alex
Langford-Smith
Jonathan D. Cooper
Jonathan D.
Cooper
Simon A. Jones
Simon
A. Jones
J. Ed Wraith
J.
Ed Wraith
Rob F. Wynn
Rob
F. Wynn
Catherine L. R. Merry
Catherine
L. R. Merry
Brian W. Bigger
Brian
W. Bigger
Significant increases in the amount and sulphation of HS in MPS brains.
Public Library of Science
2012
increases
sulphation
hs
mps
2012-04-27 01:44:34
Figure
https://plos.figshare.com/articles/figure/_Significant_increases_in_the_amount_and_sulphation_of_HS_in_MPS_brains_/316274
<p>(A) Compositional disaccharide analysis of HS from WT, MPSI, MPSIIIA and MPSIIIB brains. (B) <i>N</i>-acetlylation, <i>N</i>-, 6-<i>O</i>-, and 2-<i>O</i>-sulphate distribution within HS isolated from WT, MPSI, MPSIIIA and MPSIIIB brains. Values are calculated from the disaccharide analyses shown in A, specifying the percentage of total disaccharides along the HS chain that contain each modification. (C) Total relative amounts of HS. <b>*</b> denotes where all groups were significantly different from each other. nā=ā3 mice per group, error bars represent the SEM and p values are from one way ANOVA with Tukey's multiple comparisons test.</p>