Exon 1A deletion: <i>Gnas</i> expression and body temperature. Glenda Lassi Simon T. Ball Silvia Maggi Giovanni Colonna Thierry Nieus Cheryl Cero Alessandro Bartolomucci Jo Peters Valter Tucci 10.1371/journal.pgen.1002706.g001 https://plos.figshare.com/articles/figure/_Exon_1A_deletion_Gnas_expression_and_body_temperature_/310446 <p>(a) Representation of <i>Gnas</i> expression when the <i>Exon1A-DMR</i> (Ex1A-DMR) is methylated on the maternal (M) allele in +/+ and +/<i>Ex1a</i> or deleted on the paternal (P) allele in +/<i>Ex1a</i> mice. (b) Expression levels, by q-PCR measurements, in BAT tissue of <i>Gnas</i> (left panel) and <i>Ucp1</i> (right panel) mRNA in <i>+/+</i> versus mutant <i>+/Ex1a</i> mice. (c) Grand-averages and shadowed ± s.e.m. of body temperature over a 24-hour period for +/+ and +/<i>Ex1a</i> mice. Statistics are reported as following: <i>t</i>-test; ** = <i>P</i><0.01.</p> 2012-05-10 00:07:26 1a