Comparison between <i>ESR1</i> and ER protein on Yale breast cancer cohorts. M. BordeauxJennifer ChengHuan W. WelshAllison G. HafftyBruce R. LanninDonald WuXingyong SuNan MaXiao-Jun LuoYuling L. RimmDavid 2013 <p>The natural log of the nuclear ER AQUA score determined by QIF using SP1 is shown on the y-axis and the AQUA score for <i>ESR1</i> determined by qISH is on x-axis for YTMA 128, n = 167 with scores for both SP1 and <i>ESR1</i> (A) and YTMA 130 1993–2005 Subset, n = 195 with scores for both SP1 and <i>ESR1</i> (B). The dotted line represents the threshold for ER protein positivity. (C) Representative images from 4 cases on YTMA 128 for cytokeratin (green), DAPI (blue), and <i>ESR1</i> or ER SP1 (red).</p>