10.1371/journal.pgen.1002828.g003
Wilhelm Palm
Wilhelm
Palm
Julio L. Sampaio
Julio
L. Sampaio
Marko Brankatschk
Marko
Brankatschk
Maria Carvalho
Maria
Carvalho
Ali Mahmoud
Ali
Mahmoud
Andrej Shevchenko
Andrej
Shevchenko
Suzanne Eaton
Suzanne
Eaton
Lpp and LTP function together to mobilize lipids from the gut.
Public Library of Science
2012
ltp
mobilize
lipids
2012-07-26 00:41:11
Figure
https://plos.figshare.com/articles/figure/_Lpp_and_LTP_function_together_to_mobilize_lipids_from_the_gut_/272471
<p>(A) Immunofluorescence of a second instar larval gut, stained for Lpp, LTP and neutral lipid droplets. Lpp, LTP and lipid droplets are enriched in the same subsets of the anterior and posterior midgut. (*) indicates a nearby piece of fat body. GC: gastric caeca; AM: anterior midgut; PM: posterior midgut; HG: hindgut; MT: malpighian tubule. Scale bars = 200 µm. (B) Lipid droplets of guts from first instar wild-type and <i>mtp<sup>Δex1</sup></i> larvae, visualized with Nile red. Loss of MTP causes strong neutral lipid accumulation. Yellow: neutral lipids; red: phospholipids. GC: gastric caeca; AM: anterior midgut; PM: posterior midgut; HG: hindgut. Scale bars = 200 µm. Scale bars blow ups = 20 µm. (C) Lipid droplets of posterior midguts upon MTP, LTP or Lpp RNAi, visualized with Nile red. Knock-down of either protein causes similar accumulation of neutral lipid. Scale bars = 50 µm.</p>