GBA2 silencing reduces the IL-8 protein release in CuFi-1 cells.
Nicoletta Loberto
Maela Tebon
Ilaria Lampronti
Nicola Marchetti
Massimo Aureli
Rosaria Bassi
Maria Grazia Giri
Valentino Bezzerri
Valentina Lovato
Cinzia Cantù
Silvia Munari
Seng H. Cheng
Alberto Cavazzini
Roberto Gambari
Sandro Sonnino
Giulio Cabrini
Maria Cristina Dechecchi
10.1371/journal.pone.0104763.g006
https://plos.figshare.com/articles/figure/GBA2_silencing_reduces_the_IL_8_protein_release_in_CuFi_1_cells_/2684404
<p>CuFi-1 cells were transfected with GBA2 siRNA or scrambled oligonucleotides and then infected with PAO1 as indicated in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0104763#pone-0104763-g005" target="_blank">figure 5</a>. The supernatants were collected at the end of infection, and IL-8 protein release was measured as detailed in the “Methods” section. The data reported are the mean ± SE of eight independent experiments performed in duplicate. Comparisons between groups were made by using Student’s <i>t</i> tests.</p>
2014-08-20 18:09:01
Genz
GBA 2 activity
miglustat
F 508del chloride channel activity
CF
infection
aeruginosa
GBA 2
SL
IL