GBA2 silencing reduces the IL-8 protein release in CuFi-1 cells. Nicoletta Loberto Maela Tebon Ilaria Lampronti Nicola Marchetti Massimo Aureli Rosaria Bassi Maria Grazia Giri Valentino Bezzerri Valentina Lovato Cinzia Cantù Silvia Munari Seng H. Cheng Alberto Cavazzini Roberto Gambari Sandro Sonnino Giulio Cabrini Maria Cristina Dechecchi 10.1371/journal.pone.0104763.g006 https://plos.figshare.com/articles/figure/GBA2_silencing_reduces_the_IL_8_protein_release_in_CuFi_1_cells_/2684404 <p>CuFi-1 cells were transfected with GBA2 siRNA or scrambled oligonucleotides and then infected with PAO1 as indicated in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0104763#pone-0104763-g005" target="_blank">figure 5</a>. The supernatants were collected at the end of infection, and IL-8 protein release was measured as detailed in the “Methods” section. The data reported are the mean ± SE of eight independent experiments performed in duplicate. Comparisons between groups were made by using Student’s <i>t</i> tests.</p> 2014-08-20 18:09:01 Genz GBA 2 activity miglustat F 508del chloride channel activity CF infection aeruginosa GBA 2 SL IL