Sch B inhibits Dox induced NADPH oxidase subunits.
Rajarajan A. Thandavarayan
Vijayasree V. Giridharan
Somasundaram Arumugam
Kenji Suzuki
Kam Ming Ko
Prasanna Krishnamurthy
Kenichi Watanabe
Tetsuya Konishi
10.1371/journal.pone.0119214.g008
https://plos.figshare.com/articles/figure/Sch_B_inhibits_Dox_induced_NADPH_oxidase_subunits_/2674039
<p>(A–D) Representative Western immunoblots and densitometry analysis using Scion image software for p47phox, p67phox and gp91phox in group N, group V and Sch B treated mice; Blots were normalized against GAPDH. Each bar represents means ± S.E. (n = 3–5). **<i>P <</i> 0.01 vs. group N mice; <sup>#</sup><i>P <</i> 0.05 and <sup>##</sup><i>P <</i> 0.01 vs. group V mice.</p>
2015-03-05 15:01:36
NADPH oxidase subunits
cardiomyocyte DNA damage
Sch B treatment
mitogen kinase 2 levels
LV proinflammatory cytokines
Doxorubicin Induced Cardiac Dysfunction
Sch B
expression
Sch B treatment mice
Schisandrin B
reactive oxygen species
IP
MAPK