Homeostatic proliferation of OT-I/DNRII is MHC I dependent. Lisa D. S. Johnson Stephen C. Jameson 10.1371/journal.pone.0042268.g005 https://plos.figshare.com/articles/figure/_Homeostatic_proliferation_of_OT_I_DNRII_is_MHC_I_dependent_/267138 <p>CFSE labeled CD44<sup>lo</sup> OT-I Rag<sup>−/−</sup> or OT-I/DNRII Rag<sup>−/−</sup> CD8 T cells were transferred into irradiated K<sup>b</sup>D<sup>b−/−</sup> or wild-type hosts. One week later, lymph nodes and spleen from sacrificed mice were pooled and analyzed. (<b>A</b>) Representative CFSE dilution histograms of OT-I and OT-I/DNRII CD8 T cells in pooled lymph nodes and spleen one week after transfer into irradiated B6 and K<sup>b</sup>D<sup>b−/−</sup> hosts. (<b>B</b>) Recovery of OT-I and OT-I/DNRII CD8 T cells after one week in irradiated B6 or K<sup>b</sup>D<sup>b−/−</sup> hosts. Each symbol represents an individual mouse. Results are presented as the combination of three independent experiments.</p> 2012-08-06 01:58:58 proliferation mhc