10.1371/journal.pone.0147951.s001
Anna K. Kraus
Anna
K. Kraus
Jin Chen
Jin
Chen
Ilka Edenhofer
Ilka
Edenhofer
Inga Ravens
Inga
Ravens
Ariana Gaspert
Ariana
Gaspert
Pietro E. CippĂ
Pietro
E. CippĂ
Steffen Mueller
Steffen
Mueller
Rudolf P. Wuthrich
Rudolf
P. Wuthrich
Stephan Segerer
Stephan
Segerer
Guenter Bernhardt
Guenter
Bernhardt
Thomas Fehr
Thomas
Fehr
Absence of DNAM-1 ligands does not prolong skin allograft survival.
Public Library of Science
2016
ligands CD 112
T Cell Costimulation
CD 155
CD 112
Kidney Transplantation DNAX accessory protein
mouse kidney transplantation model
DNAM
allospecific T cell response
2016-02-03 22:27:20
Figure
https://plos.figshare.com/articles/figure/The_Role_of_T_Cell_Costimulation_via_DNAM_1_in_Kidney_Transplantation/2607247
<p>(A) Skin grafts from fully MHC-mismatched WT BALB/c (n = 19) or CD155 KO (n = 24) donors were performed on B6 recipients. Median survival time: 9 vs. 10 days (WT vs. CD155 KO). (B) Skin grafts from WT BALB/c (n = 7) or CD155 KO (n = 8) donors were performed on minor antigen mismatched DBA/2 recipients. Median survival time: 13 vs. 15 days (WT vs. CD155 KO). (C) Skin grafts from fully MHC-mismatched WT B6 (n = 8) or CD112 KO (n = 8) donors were performed on CBA recipients. Median survival time: 11 vs. 12 days (WT vs. CD112 KO). (D) Skin grafts from MHC I antigen mismatched B6 (n = 7) or CD112 (n = 8) donors were performed on bm1 recipients. Median survival time: 25.5 vs. 21 days (WT vs. CD112 KO, P = 0.01).</p> <p>(TIF)</p>