Host versus pathogen control of <i>LRRK2</i> expression levels.
Vinicius M. Fava
Jérémy Manry
Aurélie Cobat
Marianna Orlova
Nguyen Van Thuc
Nguyen Ngoc Ba
Vu Hong Thai
Laurent Abel
Alexandre Alcaïs
Erwin Schurr
10.1371/journal.pntd.0004412.g003
https://plos.figshare.com/articles/figure/Host_versus_pathogen_control_of_i_LRRK2_i_expression_levels_/2602786
<p><i>LRRK2</i> expression levels for 53 unrelated subjects are indicated on the y-axis and stratified according to rs2404580 genotypes on the x-axis. The left panel represents baseline expression while the right panel indicates gene expression levels following stimulation with <i>M</i>. <i>leprae</i> antigen.</p>
2016-02-04 21:45:09
Missense LRRK 2 Variant
LRRK 2 missense variant M 2397T
LRRK 2 locus
M 2397T variant
T 1R LRRK 2 involvement
T 1R SNPs
LRRK 2
LRRK 2 gene encodes
T 1R susceptibility.MethodologyAn association scan
LRRK 2 protein turnover
T 1R association
LRRK 2 gene transcriptional levels.Principal FindingsA
Mycobacterium leprae antigen.SignificanceThe results support
T 1R families
LRRK 2 gene
LRRK 2 variants
T 1R
LRRK 2 availability
18 T 1R variants
T 1R susceptibility gene