Host versus pathogen control of <i>LRRK2</i> expression levels. Vinicius M. Fava Jérémy Manry Aurélie Cobat Marianna Orlova Nguyen Van Thuc Nguyen Ngoc Ba Vu Hong Thai Laurent Abel Alexandre Alcaïs Erwin Schurr 10.1371/journal.pntd.0004412.g003 https://plos.figshare.com/articles/figure/Host_versus_pathogen_control_of_i_LRRK2_i_expression_levels_/2602786 <p><i>LRRK2</i> expression levels for 53 unrelated subjects are indicated on the y-axis and stratified according to rs2404580 genotypes on the x-axis. The left panel represents baseline expression while the right panel indicates gene expression levels following stimulation with <i>M</i>. <i>leprae</i> antigen.</p> 2016-02-04 21:45:09 Missense LRRK 2 Variant LRRK 2 missense variant M 2397T LRRK 2 locus M 2397T variant T 1R LRRK 2 involvement T 1R SNPs LRRK 2 LRRK 2 gene encodes T 1R susceptibility.MethodologyAn association scan LRRK 2 protein turnover T 1R association LRRK 2 gene transcriptional levels.Principal FindingsA Mycobacterium leprae antigen.SignificanceThe results support T 1R families LRRK 2 gene LRRK 2 variants T 1R LRRK 2 availability 18 T 1R variants T 1R susceptibility gene