10.1371/journal.pntd.0004412.g003
Vinicius M. Fava
Vinicius
M. Fava
Jérémy Manry
Jérémy
Manry
Aurélie Cobat
Aurélie
Cobat
Marianna Orlova
Marianna
Orlova
Nguyen Van Thuc
Nguyen
Van Thuc
Nguyen Ngoc Ba
Nguyen
Ngoc Ba
Vu Hong Thai
Vu
Hong Thai
Laurent Abel
Laurent
Abel
Alexandre Alcaïs
Alexandre
Alcaïs
Erwin Schurr
Erwin
Schurr
Host versus pathogen control of <i>LRRK2</i> expression levels.
Public Library of Science
2016
Missense LRRK 2 Variant
LRRK 2 missense variant M 2397T
LRRK 2 locus
M 2397T variant
T 1R LRRK 2 involvement
T 1R SNPs
LRRK 2
LRRK 2 gene encodes
T 1R susceptibility.MethodologyAn association scan
LRRK 2 protein turnover
T 1R association
LRRK 2 gene transcriptional levels.Principal FindingsA
Mycobacterium leprae antigen.SignificanceThe results support
T 1R families
LRRK 2 gene
LRRK 2 variants
T 1R
LRRK 2 availability
18 T 1R variants
T 1R susceptibility gene
2016-02-04 21:45:09
Figure
https://plos.figshare.com/articles/figure/Host_versus_pathogen_control_of_i_LRRK2_i_expression_levels_/2602786
<p><i>LRRK2</i> expression levels for 53 unrelated subjects are indicated on the y-axis and stratified according to rs2404580 genotypes on the x-axis. The left panel represents baseline expression while the right panel indicates gene expression levels following stimulation with <i>M</i>. <i>leprae</i> antigen.</p>