%0 Figure %A Yoon, Ji-Ae %A Han, Dong-Hee %A Noh, Jong-Yun %A Kim, Mi-Hee %A Son, Gi Hoon %A Kim, Kyungjin %A Kim, Chang-Ju %A Kim Pak, Youngmi %A Cho, Sehyung %D 2012 %T Experimental scheme. %U https://plos.figshare.com/articles/figure/_Experimental_scheme_/256825 %R 10.1371/journal.pone.0044053.g001 %2 https://plos.figshare.com/ndownloader/files/586341 %K diabetes and endocrinology %K Mental health %K physiology %X

Young adult C57BL/6J male mice (8 weeks old) were first entrained to a 12∶12 LD photoperiodic cycle for two weeks with food and water available ad libitum. Then mice were randomly divided into three groups: food available ad libitum (AF), food available during the late day (ZT 6 to 11) (DF), and food available during the late night (ZT 18 to 23) (NF) with water available all the time. This time-restrictive feeding regimen was maintained either up to the end of each experiment or for 4 weeks and then returned to ad libitum feeding (Figure 2 and 3). Gray bar indicates major meal time of normal adult mouse (Figure S1A).

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