Li, Dan-Dan Sun, Ting Wu, Xiao-Qi Chen, Shu-Peng Deng, Rong Jiang, Shan Feng, Gong-Kan Pan, Jing-Xuan Zhang, Xiao-Shi Zeng, Yi-Xin Zhu, Xiao-Feng Topotecan treatment triggers autophagy in colon cancer cells. <p><b>A.</b> HCT116, LS-174T and HT29 cells were transfected for 24 h with an expression construct encoding LC3 fused to the yellow fluorescent protein (YFP-LC3). Thereafter, the cells were treated with or without 1 µg/mL topotecan (TPT) for 24 h and visualised under a confocal microscope. <b>B.</b> The indicated cells were treated with the indicated concentrations of topotecan for 24 h. The lysates were analysed by immunoblotting with The LC3 and P62 antibodies.</p> triggers;autophagy;colon;cancer 2012-09-14
    https://plos.figshare.com/articles/figure/_Topotecan_treatment_triggers_autophagy_in_colon_cancer_cells_/246346
10.1371/journal.pone.0045058.g001