10.1371/journal.pone.0047361.g007 Troy A. Luster Troy A. Luster Ipsita Mukherjee Ipsita Mukherjee Jeffrey A. Carrell Jeffrey A. Carrell Yun Hee Cho Yun Hee Cho Jeffrey Gill Jeffrey Gill Lizbeth Kelly Lizbeth Kelly Andy Garcia Andy Garcia Christopher Ward Christopher Ward Luke Oh Luke Oh Stephen J. Ullrich Stephen J. Ullrich Thi-Sau Migone Thi-Sau Migone Robin Humphreys Robin Humphreys BLyS-gel inhibits MCL growth <i>in vivo</i> in a dose-dependent manner. Public Library of Science 2012 inhibits mcl dose-dependent 2012-10-09 00:46:27 Figure https://plos.figshare.com/articles/figure/_BLyS_gel_inhibits_MCL_growth_in_vivo_in_a_dose_dependent_manner_/232787 <p>Rec-1 cells (1Ɨ10<sup>6</sup>) were injected into the tail veins of SCID mice on day 0. <b>A.</b> Mice were divided into five groups (nā€Š=ā€Š10) for i.v. treatment with BLyS-gel at 2, 0.5, or 0.1 mg/kg; free gelonin at 2 mg/kg; or an equivalent volume of vehicle. All groups were injected with 10F4 at 5 mg/kg to deplete circulating mBLyS on day 1, and treatments began on day 2. Treatments were given twice per week for six weeks. Additional 10F4 was given prior to each week of treatment. P values refer to results of the Logrank test. <b>B.</b> Spleens weights at time of sacrifice. P value refers to results of the student's t test.</p>