10.1371/journal.pone.0047361.g007
Troy A. Luster
Troy
A. Luster
Ipsita Mukherjee
Ipsita
Mukherjee
Jeffrey A. Carrell
Jeffrey
A. Carrell
Yun Hee Cho
Yun
Hee Cho
Jeffrey Gill
Jeffrey
Gill
Lizbeth Kelly
Lizbeth
Kelly
Andy Garcia
Andy
Garcia
Christopher Ward
Christopher
Ward
Luke Oh
Luke
Oh
Stephen J. Ullrich
Stephen
J. Ullrich
Thi-Sau Migone
Thi-Sau
Migone
Robin Humphreys
Robin
Humphreys
BLyS-gel inhibits MCL growth <i>in vivo</i> in a dose-dependent manner.
Public Library of Science
2012
inhibits
mcl
dose-dependent
2012-10-09 00:46:27
Figure
https://plos.figshare.com/articles/figure/_BLyS_gel_inhibits_MCL_growth_in_vivo_in_a_dose_dependent_manner_/232787
<p>Rec-1 cells (1Ć10<sup>6</sup>) were injected into the tail veins of SCID mice on day 0. <b>A.</b> Mice were divided into five groups (nā=ā10) for i.v. treatment with BLyS-gel at 2, 0.5, or 0.1 mg/kg; free gelonin at 2 mg/kg; or an equivalent volume of vehicle. All groups were injected with 10F4 at 5 mg/kg to deplete circulating mBLyS on day 1, and treatments began on day 2. Treatments were given twice per week for six weeks. Additional 10F4 was given prior to each week of treatment. P values refer to results of the Logrank test. <b>B.</b> Spleens weights at time of sacrifice. P value refers to results of the student's t test.</p>