10.1371/journal.pone.0047472.g009
Sandeep S. Patil
Sandeep
S. Patil
Ivaylo Gentschev
Ivaylo
Gentschev
Marion Adelfinger
Marion
Adelfinger
Ulrike Donat
Ulrike
Donat
Michael Hess
Michael
Hess
Stephanie Weibel
Stephanie
Weibel
Ingo Nolte
Ingo
Nolte
Alexa Frentzen
Alexa
Frentzen
Aladar A. Szalay
Aladar
A. Szalay
Presence of immune cells in tumors of STSA-1 xenografted mice 7 days after GLV-1h68-, GLV-1h109- or PBS-treatments.
Public Library of Science
2012
cells
tumors
stsa-1
xenografted
mice
days
glv-1h109-
2012-10-16 02:32:58
Figure
https://plos.figshare.com/articles/figure/_Presence_of_immune_cells_in_tumors_of_STSA_1_xenografted_mice_7_days_after_GLV_1h68_GLV_1h109_or_PBS_treatments_/229178
<p>Percentage of (A) Gr-1<sup>high</sup>CD11b<sup>+</sup> (MDSCs, granulocytes), (B) Gr-1<sup>int</sup>CD11b<sup>+</sup> (MDSCs, monocytes), (C) F4/80<sup>+</sup>CD45<sup>+</sup> (macrophages) or (D) MHCII<sup>+</sup>CD45<sup>+</sup> (mainly B cells, macrophages and dendritic cells) cells in tumors of STSA-1 xenografted mice. Experiments were done twice with at least 3 mice per group. The data are presented as mean values +/- SD. The statistical significance was analyzed using one-way ANOVA followed Bonferronìs multiple comparison test (***P<0.001, **P<0.01, *P<0.05). The Anti-Gr-1 mAb (RB6-8C5) has long been used to stain MDSCs and allows the distinction of at least two subsets of granulocytes (Gr-1<sup>high</sup>CD11b<sup>+</sup>) and monocytic cells (Gr-1<sup>int</sup>CD11b<sup>+</sup>).</p>