Partial CLUSTAL 2.1 multiple sequence alignment of publicly available <i>Brugia malayi</i> (Bm1_48165), <i>Homo sapiens</i> (<i>Hs</i>SAH), <i>Saccharomyces cerevisiae</i> (<i>Sc</i>SAH), and our cloned <i>Brugia malayi</i> (<i>Bm</i>SAH) S-adenosyl homocysteinases, showing the “insert” missing from the publicly available nematode protein sequence. Elizabeth Bilsland Daniel M. Bean Eileen Devaney Stephen G. Oliver 10.1371/journal.pntd.0004401.g002 https://plos.figshare.com/articles/figure/_Partial_CLUSTAL_2_1_multiple_sequence_alignment_of_publicly_available_Brugia_malayi_Bm1_48165_Homo_sapiens_Hs_SAH_Saccharomyces_cerevisiae_Sc_SAH_and_our_cloned_Brugia_malayi_Bm_SAH_S_adenosyl_homocysteinases_showing_the_insert_missing_from_the_publicly_/1642733 <p>The absence of the 27 amino acids in the publicly available <i>Brugia</i> sequence (Bm1_48165) could indicate a splice variant of the enzyme or simply a problem with the genome assembly.</p> 2016-01-28 12:42:23 World Health Organization filarial compound aid antihelmintic drug development Brugia malayi drug targets contracting lymphatic filariasis complement yeast deletions Identify Novel Compounds Brugia malayi BackgroundLymphatic filariasis strain parasite enzymes worms Wuchereria bancrofti Brugia malayi enzymes