Sliding window correlation (SWC) to identify GO terms associated with serum neutralization titers. Richard C. Laughlin Kenneth L. Drake John C. Morrill L. Garry Adams 10.1371/journal.pone.0147027.g008 https://plos.figshare.com/articles/figure/_Sliding_window_correlation_SWC_to_identify_GO_terms_associated_with_serum_neutralization_titers_/1638987 <p>(<b>A</b>) Immunologically important GO terms correlated with log10(PRNT<sub>80</sub>) listed by time window with associated p-value indicated significance of correlation. (<b>B</b>) Correlated GO terms plotted as log10(PRNT<sub>80</sub>) vs Normalized GO term DBGGA Bayesian z-scores. The GO term <i>Viral life cycle</i> had a negative correlation with seroconversion at the windowed time points –6, –5, and –4 pSN (upper panel), while <i>Positive regulation of T cell cytokine production</i> shows a positive correlation with seroconversion at the windowed time points –4, –3, and –2 pSN (lower panel).</p> 2016-01-28 12:37:42 arMP -12. RVF Correlative Gene Expression negative-stranded RNA virus time course RNAs Rift Valley fever serum neutralizing antibody responses Additional bioinformatic analyses vaccine vaccination RVFV Rift Valley Fever Vaccinates Rift Valley fever Virus immunity 21 days vector-borne zoonotic disease