10.1371/journal.pone.0147013.g003 Ximi K. Wang Ximi K. Wang Monica Agarwal Monica Agarwal Nataliya Parobchak Nataliya Parobchak Alex Rosen Alex Rosen Anna M. Vetrano Anna M. Vetrano Aarthi Srinivasan Aarthi Srinivasan Bingbing Wang Bingbing Wang Todd Rosen Todd Rosen The effects of MEHP exposure on interaction of RelB/p52 with the <i>CRH/COX-2</i> gene promoters. Public Library of Science 2016 Human Placenta Women phthalate metabolites gene activity crh mehp preterm birth mechanism cox relb Protein abundance pathway 2016-01-18 15:12:56 Figure https://plos.figshare.com/articles/figure/_The_effects_of_MEHP_exposure_on_interaction_of_RelB_p52_with_the_CRH_COX_2_gene_promoters_/1635617 <p>Term cytotrophoblast were exposed to MEHP for 24 hrs at concentrations as indicated. ChIP assays were performed to determine occupancy of RelB/p52 at <i>CRH</i> (<b>A</b>) and <i>COX-2</i> (<b>B</b>), and also occupancy of RelA at the <i>CRH</i> (<b>C</b>) and <i>COX-2</i> (<b>D</b>) gene promoter. Fold enrichment was derived with normalization to a human DNA a satellite, a non-coding DNA sequence to which no transcriptional factors should bind. Rabbit IgG was used as a non-specific control. The bars indicate the average of fold enrichment with error bars representing the standard deviation from three independent experiments. * p < 0.01.</p>