10.1371/journal.pone.0147013.g003
Ximi K. Wang
Ximi K.
Wang
Monica Agarwal
Monica
Agarwal
Nataliya Parobchak
Nataliya
Parobchak
Alex Rosen
Alex
Rosen
Anna M. Vetrano
Anna
M. Vetrano
Aarthi Srinivasan
Aarthi
Srinivasan
Bingbing Wang
Bingbing
Wang
Todd Rosen
Todd
Rosen
The effects of MEHP exposure on interaction of RelB/p52 with the <i>CRH/COX-2</i> gene promoters.
Public Library of Science
2016
Human Placenta Women
phthalate metabolites
gene activity
crh
mehp
preterm birth
mechanism
cox
relb
Protein abundance
pathway
2016-01-18 15:12:56
Figure
https://plos.figshare.com/articles/figure/_The_effects_of_MEHP_exposure_on_interaction_of_RelB_p52_with_the_CRH_COX_2_gene_promoters_/1635617
<p>Term cytotrophoblast were exposed to MEHP for 24 hrs at concentrations as indicated. ChIP assays were performed to determine occupancy of RelB/p52 at <i>CRH</i> (<b>A</b>) and <i>COX-2</i> (<b>B</b>), and also occupancy of RelA at the <i>CRH</i> (<b>C</b>) and <i>COX-2</i> (<b>D</b>) gene promoter. Fold enrichment was derived with normalization to a human DNA a satellite, a non-coding DNA sequence to which no transcriptional factors should bind. Rabbit IgG was used as a non-specific control. The bars indicate the average of fold enrichment with error bars representing the standard deviation from three independent experiments. * p < 0.01.</p>