A model of the interaction of DR5026 with a bacterial membrane. Natalya Panova Eva Zborníková Ondřej Šimák Radek Pohl Milan Kolar Katerina Bogdanova Renata Vecerova Gabriela Seydlová Radovan Fiser Romana Hadravová Hana Šanderová Dragana Vítovská Michaela Šiková Tomáš Látal Petra Lovecká Ivan Barvík Libor Krásný Dominik Rejman 10.1371/journal.pone.0145918.g009 https://plos.figshare.com/articles/figure/_A_model_of_the_interaction_of_DR5026_with_a_bacterial_membrane_/1630221 <p>The final state of MD simulation after 55 ns shows <b>DR5026</b> molecules penetrated into the phospholipid bilayer. The nitrogen atoms from the iminosugar modules of <b>DR5026</b> are highlighted as blue spheres. Phosphorus atoms of the phospholipid bilayer (PB) are depicted as yellow/red spheres. For clarity, almost all atoms of the PB are hidden.</p> 2016-01-05 14:53:52 strain transepithelial transport Bactericidal Lipophosphonoxins cell disintegration Ames test bactericidal concentrations LPPOs compound plasmatic membrane acidic environment