10.1371/journal.pone.0143063.g004
Wafa Markikou-Ouni
Wafa
Markikou-Ouni
Sima Drini
Sima
Drini
Narges Bahi-Jaber
Narges
Bahi-Jaber
Mehdi Chenik
Mehdi
Chenik
Amel Meddeb-Garnaoui
Amel
Meddeb-Garnaoui
Effect of LipESP on LPS-, IFN-γ-, or IFN-γ/LPS-induced cytokine production by human monocytes.
Public Library of Science
2015
CD 40 expression
CD 86 surface expression
maturation
T cell activation
lps
monocyte
LiP 15
LipESP
Human Dendritic Cells Differentiation
DCs differentiation
elongation factor 1
protein
Maturation Leishmania parasites
tnf
il
CD 1a LiP 23
ifn
Leishmania infantum
2015-11-18 03:36:00
Figure
https://plos.figshare.com/articles/figure/_Effect_of_LipESP_on_LPS_IFN_947_or_IFN_947_LPS_induced_cytokine_production_by_human_monocytes_/1606806
<p>Production of (a) IL-12p70, (b) IL-10 and (c) TNF-α were measured in monocytes supernatant by ELISA after 24 h of stimulation by LipESP in presence or absence of LPS (for IL-10 and TNF-α analysis) or after 12 h of priming with IFN-γ followed by 24 additional hours of stimulation by LipESP with or without LPS co-treatment (for IL-12 analysis). Results are expressed as mean ± standard deviation (n = 9). * Statistically significant difference between non stimulated and LipESP-, LPS-, and IFN-γ/LPS-stimulated monocytes (p<0·05); ** Statistically significant difference between IFN-γ stimulated and LipESP/IFN-γ-co-treated monocytes (p<0·05) for IL-12p70 and between LPS-stimulated and LipESP-LPS-co-treated monocytes (p<0·05) for IL-10 and TNF-α; *** Statistically significant difference between IFN-γ/LPS stimulated and LipESP/IFN-γ/LPS-co-treated monocytes (p<0·05).</p>