Effect of PMBPs on NFκB activity and MAPK pathways.
Jia Liu
Jing Bai
Guoqiang Jiang
Xinli Li
Jing Wang
Dachang Wu
Lawrence Owusu
Ershao Zhang
Weiling Li
10.1371/journal.pone.0142157.g008
https://plos.figshare.com/articles/figure/_Effect_of_PMBPs_on_NF_954_B_activity_and_MAPK_pathways_/1595169
<p>(A,B) The cells were treated with PMBPs (0, 5, 10, 25 μg/ml) for 24 h. Cell lysates were prepared and subjected to Western blot analysis. The protein level of nuclear p65, p-IκBα, IκBα, p-ERK, p-p38 and p-JNK were measured. (C,D) Histograms show mean (±SD) level of nuclear p65, p-IκBα, IκBα, p-ERK, p-p38 and p-JNK from three independent experiments. The nuclear p65, p-IκBα, IκBα, p-ERK, p-p38 and p-JNK expression levels were expressed relative to loading control β-Actin and standardized to the non-treated control group. *<i>P<0</i>.<i>05</i> and **<i>P<0</i>.<i>01</i> compared to the control group.</p>
2015-11-05 03:38:14
p 38 MAPK
activation
Pinus massoniana bark
cancer cells
PMBP
Pinus massoniana Bark Proanthocyanidins
transwell chamber assays
Cell Migration Pinus massoniana bark proanthocyanidins
nf
mmp
erk