Liu, Jia Bai, Jing Jiang, Guoqiang Li, Xinli Wang, Jing Wu, Dachang Owusu, Lawrence Zhang, Ershao Li, Weiling PMBPs suppress MMP-9 activity and expression. <p>The cells were treated with PMBPs (0, 5, 10, 25 μg/ml) for 24 h. (A) Activity of MMP-9 in the cell supernatant at various concentrations of PMBPs was examined by gelatin zymography assay. The white bands represent MMP-9 mediated gelatin digestion. (B) The protein expression of MMP-9 in A2780 cells at various concentrations of PMBPs was evaluated by Western blot. Histogram shows mean level of MMP-9 (±SD) from three independent experiments. MMP-9 protein level was expressed relative to loading control, β-Actin, and standardized to the non-treated control group. *<i>P<0</i>.<i>05</i> and **<i>P<0</i>.<i>01</i> compared to the control group.</p> p 38 MAPK;activation;Pinus massoniana bark;cancer cells;PMBP;Pinus massoniana Bark Proanthocyanidins;transwell chamber assays;Cell Migration Pinus massoniana bark proanthocyanidins;nf;mmp;erk 2015-11-05
    https://plos.figshare.com/articles/figure/_PMBPs_suppress_MMP_9_activity_and_expression_/1595168
10.1371/journal.pone.0142157.g007