%0 Figure %A Kumar, J. Dinesh %A Holmberg, Chris %A Balabanova, Silvia %A Borysova, Lyudmyla %A Burdyga, Ted %A Beynon, Robert %A Dockray, Graham J. %A Varro, Andrea %D 2015 %T Effects of IGF and chemerin on Ca2+ signalling in MSCs. %U https://plos.figshare.com/articles/figure/_Effects_of_IGF_and_chemerin_on_Ca_2_signalling_in_MSCs_/1589259 %R 10.1371/journal.pone.0141331.g002 %2 https://plos.figshare.com/ndownloader/files/2389044 %K TGF βig %K adhesion %K receptor tyrosine kinase stimulant %K exocytosi %K igf %K Mesenchymal Stem Cells Exhibit Regulated Exocytosis %K secretory protein transport %K secretion %K chemerin %K mmp %K gene ontology analysis %K exhibit %K preformed secretory vesicles %K msc %X

A. Images of Fluo-4 loaded MSCs taken in the absence (left) and the presence (right) of chemerin (100nM), respectively. B. IGF-II (100 ng.ml-1, top) and chemerin (100nM, Ch) induce Ca2+ oscillations in Fluo-4 loaded cells. C. Relaxation of Ca2+ transients induced by chemerin or IGF-II after removal of external Ca2+ (Ca2+ free solution with 2mM EGTA).

%I PLOS ONE