Effects of IGF and chemerin on Ca<sup>2+</sup> signalling in MSCs. J. Dinesh Kumar Chris Holmberg Silvia Balabanova Lyudmyla Borysova Ted Burdyga Robert Beynon Graham J. Dockray Andrea Varro 10.1371/journal.pone.0141331.g002 https://plos.figshare.com/articles/figure/_Effects_of_IGF_and_chemerin_on_Ca_2_signalling_in_MSCs_/1589259 <p><i>A</i>. Images of Fluo-4 loaded MSCs taken in the absence (left) and the presence (right) of chemerin (100nM), respectively. <i>B</i>. IGF-II (100 ng.ml<sup>-1</sup>, top) and chemerin (100nM, Ch) induce Ca<sup>2+</sup> oscillations in Fluo-4 loaded cells. <i>C</i>. Relaxation of Ca<sup>2+</sup> transients induced by chemerin or IGF-II after removal of external Ca<sup>2+</sup> (Ca<sup>2+</sup> free solution with 2mM EGTA).</p> 2015-10-29 03:25:18 TGF βig adhesion receptor tyrosine kinase stimulant exocytosi igf Mesenchymal Stem Cells Exhibit Regulated Exocytosis secretory protein transport secretion chemerin mmp gene ontology analysis exhibit preformed secretory vesicles msc