10.1371/journal.pone.0056651.g005
Lisa Rizzetto
Lisa
Rizzetto
Gloria Giovannini
Gloria
Giovannini
Michael Bromley
Michael
Bromley
Paul Bowyer
Paul
Bowyer
Luigina Romani
Luigina
Romani
Duccio Cavalieri
Duccio
Cavalieri
Immune response to different <i>Aspergillus</i> color mutants.
Public Library of Science
2013
immunology
Infectious diseases
microbiology
2013-02-18 02:14:35
Figure
https://plos.figshare.com/articles/figure/_Immune_response_to_different_Aspergillus_color_mutants_/158075
<p>Different mutant strains elicit diverse inflammatory responses and prime peculiar adaptive T<sub>H</sub> response. (A) DCs were cultured with UV-killed conidia or hyphae for 24 hours or without any stimuli (unstimulated, us) and supernatants were used for TNFα, IL-10, IL-1β, IL-6, IL-12p70 and IL-23 measurements. Data are represented as mean+SD (N = 6), *p≤0.05, **p≤0.01, conidial mutant strains <i>vs</i> conidial WT strain; <sup>§</sup>p≤0.05, <sup>§§</sup>p≤0.01, hyphal mutant strains vs hyphal WT strain. Complete statistically significant p-values are collected in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0056651#pone.0056651.s002" target="_blank">Table S2</a>. (B,C) Healthy PBMCs were cultured with live conidia or without any stimulus, and cytokine protein and transcript levels were measured. Data are represented as mean+SD (N = 6), *p≤0.05, **p≤0.01, mutants strain <i>vs</i> WT strain.</p>