Kumar Yadav, Mukesh Young Go, Yoon Chae, Sung-Won Song, Jae-Jun Confocal microscopic images of <i>Streptococcus pneumoniae</i> D39 biofilms grown with and without pyrimidinedione. <p><b>(</b>A & B) Representative confocal images of a control sample. The biofilms in the control sample were thick with an organized 3-dimesional structure. <b>(</b>C & D) Representative confocal images of biofilms grown with 7 μM/ml pyrimidinedione. The pyrimidinedione-grown biofilms were thin and disorganized, with clumps of cells attached to the bottom of plate.</p> Small Molecule DAM Inhibitor;cck;Streptococcus pneumoniae D 39;pneumococcal biofilm growth;novel antimicrobial compounds;gene expression;planktonic cell growth;host defense systems;microarray analysis;gene expression profiles;scanning electron microscopy analysis;amc;molecule Dam inhibitor;study gene expression;middle ear epithelium cell line;mssa;extracellular polysaccharide matrix;biofilm formation;exhibit eukaryotic cell toxicity;Staphylococcus epidermidis biofilm growth;scanning electron microscopy;confocal microscopy analysis;microtiter plate assay;Vitro Streptococcus pneumoniae;DNA adenine methyltransferase;mrsa;pyrimidinedione;Streptococcus pneumoniae biofilm formation;Disrupts Streptococcus pneumoniae Biofilm Growth 2015-10-02
    https://plos.figshare.com/articles/figure/_Confocal_microscopic_images_of_Streptococcus_pneumoniae_D39_biofilms_grown_with_and_without_pyrimidinedione_/1562987
10.1371/journal.pone.0139238.g007