10.1371/journal.pone.0139238.g006 Mukesh Kumar Yadav Mukesh Kumar Yadav Yoon Young Go Yoon Young Go Sung-Won Chae Sung-Won Chae Jae-Jun Song Jae-Jun Song Effects of pyrimidinedione on established biofilms. Public Library of Science 2015 Small Molecule DAM Inhibitor cck Streptococcus pneumoniae D 39 pneumococcal biofilm growth novel antimicrobial compounds gene expression planktonic cell growth host defense systems microarray analysis gene expression profiles scanning electron microscopy analysis amc molecule Dam inhibitor study gene expression middle ear epithelium cell line mssa extracellular polysaccharide matrix biofilm formation exhibit eukaryotic cell toxicity Staphylococcus epidermidis biofilm growth scanning electron microscopy confocal microscopy analysis microtiter plate assay Vitro Streptococcus pneumoniae DNA adenine methyltransferase mrsa pyrimidinedione Streptococcus pneumoniae biofilm formation Disrupts Streptococcus pneumoniae Biofilm Growth 2015-10-02 03:23:33 Figure https://plos.figshare.com/articles/figure/_Effects_of_pyrimidinedione_on_established_biofilms_/1562983 <p>Established <i>S</i>. <i>pneumoniae</i> D39 biofilms were treated with different concentrations of pyrimidinedione. (A) Biofilm biomasses were measured by CV-microtiter plate assay. (B) Cfu counts of biofilms. The error bars represent the SD.</p>