10.1371/journal.pone.0134209.g002
Charles S. Berenson
Charles
S. Berenson
Ragina L. Kruzel
Ragina
L. Kruzel
Catherine T. Wrona
Catherine
T. Wrona
Manoj J. Mammen
Manoj
J. Mammen
Sanjay Sethi
Sanjay
Sethi
Association of TLR9 SNPs and bacterial induction of COPD ex-smoker alveolar macrophage IL-8.
Public Library of Science
2015
1237C
snp
Impaired Innate COPD Alveolar Macrophage Responses
alveolar macrophage responses
nontypeable H
dna
polymerase chain reaction
fev
nucleotide polymorphism expression
nucleotide polymorphisms
tlr
COPD alveolar macrophage responses
il
nontypeable Haemophilus influenzae
2015-09-11 04:01:55
Figure
https://plos.figshare.com/articles/figure/_Association_of_TLR9_SNPs_and_bacterial_induction_of_COPD_ex_smoker_alveolar_macrophage_IL_8_/1540572
<p>Supernatant IL-8 concentrations of alveolar macrophages, obtained from ex-smokers with COPD, incubated with nontypeable <i>Haemophilus influenzae</i> 11P6H1 (Panels A), <i>Moraxella catarrhalis</i> 6P29B1 (Panels B) and <i>Streptococcus pneumoniae</i> 25P55S1 (Panels C), were measured at 6 hours. Analysis is shown for TLR9 wildtype (dark shading) compared with TLR9 (T1237C) (light shading) on left panels. Analysis for TLR9 wildtype (dark shading) compared with TLR9 (T1486C) (striped shading) is shown in right panels. Results are shown as box plots for each group. Each box encompasses the 25<sup>th</sup> to 75<sup>th</sup> interquartile range, with the horizontal line in each box representing median values. Each vertical bar encompasses the 10<sup>th</sup> to 90<sup>th</sup> percentile ranges. Values correspond with data given in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0134209#pone.0134209.t006" target="_blank">Table 6</a>.</p>