10.1371/journal.pone.0136089.g006 Peter C. Huszthy Peter C. Huszthy Per Ø. Sakariassen Per Ø. Sakariassen Heidi Espedal Heidi Espedal Karl A. Brokstad Karl A. Brokstad Rolf Bjerkvig Rolf Bjerkvig Hrvoje Miletic Hrvoje Miletic Serum levels of selected cytokines in immunocompetent rats implanted with GBM xenografts. Public Library of Science 2015 Human Glioblastoma Cells glioblastoma patient biopsy spheroids GBM cells representative animal model ed host vivo passaging cycles tnf tumor bed immunocompetent rats cxcl leukocyte tgf cns il 2015-08-20 03:47:52 Figure https://plos.figshare.com/articles/figure/_Serum_levels_of_selected_cytokines_in_immunocompetent_rats_implanted_with_GBM_xenografts_/1515781 <p>Shown are the serum concentrations of cytokines that were consistently detected throughout the time course of the experiment. X axis indicates days from implantation (d = 0). The lines show average serum concentrations (± SEM) in the rejection group (black squares) vs. the engraftment group (open circles) of rats implanted with high generation P3 spheroids. Significant differences are denoted by asterisks (*** marks <i>P</i><0.001, * marks <i>P</i><0.05).</p>