10.1371/journal.pgen.1005434.g006
Michael S. Behnke
Michael
S. Behnke
Asis Khan
Asis
Khan
Elvin J. Lauron
Elvin
J. Lauron
John R. Jimah
John
R. Jimah
Qiuling Wang
Qiuling
Wang
Niraj H. Tolia
Niraj
H. Tolia
L. David Sibley
L. David
Sibley
Codons under positive diversifying selection encode amino acid residues at the ROP5B<sub>I</sub> /IRGa6 interface.
Public Library of Science
2015
type 8 TgCtBr 5
type 1 parasites
host immunity factors
xii
South American strains
virulence factor accounting
Virulence factors
Rhoptry Proteins ROP 5
ROP 5
North American type 2
South American type 10 VAND strain
qtl
ROP 18
Toxoplasma gondii Toxoplasma gondii
ROP 18 function
ROP 5 locus
type 10 strains
Major Murine Virulence Factors
ROP 18 knockouts
Quantitative trait locus
type 4 TgCtBr 18 strains
2015-08-20 03:46:14
Figure
https://plos.figshare.com/articles/figure/_Codons_under_positive_diversifying_selection_encode_amino_acid_residues_at_the_ROP5B_I_IRGa6_interface_/1515760
<p>(A) Structure of <i>T</i>. <i>gondii</i> ROP5B<sub>I</sub> (grey) bound to murine Irga6 (tan) showing amino acid residues under positive diversifying selection (red), ROP5B<sub>I</sub> residues at the ROP5B<sub>I</sub> /Irga6 interface (blue), and residues that are under positive diversifying selection and at the interface (purple). (B) Both panels are a rotation of 60° about the x-axis with respect to A, showing ROP5B<sub>I</sub> with Irga6 removed for clarity. The color scheme is as in A. Bottom panel is a surface representation showing the overlap in surface residues. The top panel shows the position of all amino acid residues under positive diversifying selection.</p>