The effect of age on the number of heteroplasmies in the unrelated SardiNIA sequencing project participants. DingJun SidoreCarlo J. ButlerThomas Kate WingMary QianYong MeirellesOsorio BusoneroFabio C. TsoiLam MaschioAndrea AngiusAndrea Min KangHyun NagarajaRamaiah CuccaFrancesco R. AbecasisGonçalo SchlessingerDavid 2015 <p>The number of heteroplasmies increases with age with different (colored) minor allele fraction (MAF) thresholds. Each line plots the expected number of heteroplasmies based on the Poisson loglinear model against age at an MAF threshold; while the points represent the observed mean number of heteroplasmies in each age group (<40, 40–50, 50–60, 60–70, 70–80, >80).</p>