The effect of age on the number of heteroplasmies in the unrelated SardiNIA sequencing project participants.
Jun Ding
Carlo Sidore
Thomas J. Butler
Mary Kate Wing
Yong Qian
Osorio Meirelles
Fabio Busonero
Lam C. Tsoi
Andrea Maschio
Andrea Angius
Hyun Min Kang
Ramaiah Nagaraja
Francesco Cucca
Gonçalo R. Abecasis
David Schlessinger
10.1371/journal.pgen.1005306.g005
https://plos.figshare.com/articles/figure/_The_effect_of_age_on_the_number_of_heteroplasmies_in_the_unrelated_SardiNIA_sequencing_project_participants_/1482880
<p>The number of heteroplasmies increases with age with different (colored) minor allele fraction (MAF) thresholds. Each line plots the expected number of heteroplasmies based on the Poisson loglinear model against age at an MAF threshold; while the points represent the observed mean number of heteroplasmies in each age group (<40, 40–50, 50–60, 60–70, 70–80, >80).</p>
2015-07-14 03:37:42
association
body mass index
heteroplasmie
Assessing Mitochondrial DNA Variation
heteroplasmy
homoplasmie
mtDNA copy numbers
copy number
mtDNA copy number
sequencing error rates
Tailored Sequencing Analysis Tools DNA sequencing
variant