%0 Figure %A Cattò, Cristina %A Dell’Orto, Silvia %A Villa, Federica %A Villa, Stefania %A Gelain, Arianna %A Vitali, Alberto %A Marzano, Valeria %A Baroni, Sara %A Forlani, Fabio %A Cappitelli, Francesca %D 2015 %T Synthetic scheme of compounds 23, 24, 33, 34, 35, 38. %U https://plos.figshare.com/articles/figure/_Synthetic_scheme_of_compounds_23_24_33_34_35_38_/1470193 %R 10.1371/journal.pone.0131519.g003 %2 https://plos.figshare.com/ndownloader/files/2157814 %K ZA scaffold diversity %K mass spectrometry %K approach %K nadh %K biofilm inhibition %K carboxylate anion %K Molecular Basis %K biofilm formation process %K compound zosteric acid %K Escherichia coli %K protein %K ZA derivatives %K molecule %K cinnamic acid scaffold %X

Reagents and conditions: i) from 1 for 23, from 5 for 24, from 32 for 33: H2SO4, MeOH, reflux, 1 h; ii) from 32: Py · SO3, DMF dry, 120°C, 25 min; iii) CH3I, anhydrous K2CO3, dry DMF, reflux, 1.5 h; iv) 1N NaOH, EtOH.

%I PLOS ONE