%0 Generic %A Stein, Claudia %A Makarewicz, Oliwia %A A. Bohnert, Jürgen %A Pfeifer, Yvonne %A Kesselmeier, Miriam %A Hagel, Stefan %A W. Pletz, Mathias %D 2015 %T Results of susceptibility testing (MICs), the molecular analyses of β-lactamases and porins, the efflux properties (EHT), and the synergism testing (FICIs). %U https://plos.figshare.com/articles/dataset/_Results_of_susceptibility_testing_MICs_the_molecular_analyses_of_946_lactamases_and_porins_the_efflux_properties_EHT_and_the_synergism_testing_FICIs_/1446440 %R 10.1371/journal.pone.0126479.t001 %2 https://plos.figshare.com/ndownloader/files/2107241 %K mic %K resistance %K ompK %K combination %K antibiotic %K tigecycline %K Klebsiella pneumoniae Carbapenemase %K kpc %K colistin %K mortality rates %K infection %K strain %K mechanism %K Dimensional Checkerboard Synergy Analysis %X

The EHT and the FICI values are given as median ± standard deviation. Synergistic FICI values are indicated in bold letters. The FICI values indicated in brackets represent the lowest values for the given combination.

*Strains were obtained from: NRZ = National Reference Laboratory for multidrug-resistant gram-negative bacteria, Ruhr-University Bochum, Germany, and RKI = Robert-Koch-Institut, Wernigerode, Germany; MEM = meropenem; CST = colistin; TCG = tigecycline; FICI = fractional inhibitory concentration index; EHT = efflux half-time; nm = not measureable; aa = amino acid;:: = gene dispuption by insertion sequence; del = deletion; ins insertion; sub = substitution;

**non-functional (STOP mutation in blaOXA-9 gene)

Results of susceptibility testing (MICs), the molecular analyses of β-lactamases and porins, the efflux properties (EHT), and the synergism testing (FICIs).

%I PLOS ONE