10.1371/journal.pone.0126479.t001
Claudia Stein
Claudia
Stein
Oliwia Makarewicz
Oliwia
Makarewicz
Jürgen A. Bohnert
Jürgen
A. Bohnert
Yvonne Pfeifer
Yvonne
Pfeifer
Miriam Kesselmeier
Miriam
Kesselmeier
Stefan Hagel
Stefan
Hagel
Mathias W. Pletz
Mathias
W. Pletz
Results of susceptibility testing (MICs), the molecular analyses of β-lactamases and porins, the efflux properties (EHT), and the synergism testing (FICIs).
Public Library of Science
2015
mic
resistance
ompK
combination
antibiotic
tigecycline
Klebsiella pneumoniae Carbapenemase
kpc
colistin
mortality rates
infection
strain
mechanism
Dimensional Checkerboard Synergy Analysis
2015-06-11 03:00:26
Dataset
https://plos.figshare.com/articles/dataset/_Results_of_susceptibility_testing_MICs_the_molecular_analyses_of_946_lactamases_and_porins_the_efflux_properties_EHT_and_the_synergism_testing_FICIs_/1446440
<p>The EHT and the FICI values are given as median ± standard deviation. Synergistic FICI values are indicated in bold letters. The FICI values indicated in brackets represent the lowest values for the given combination.</p><p>*Strains were obtained from: NRZ = National Reference Laboratory for multidrug-resistant gram-negative bacteria, Ruhr-University Bochum, Germany, and RKI = Robert-Koch-Institut, Wernigerode, Germany; MEM = meropenem; CST = colistin; TCG = tigecycline; FICI = fractional inhibitory concentration index; EHT = efflux half-time; nm = not measureable; aa = amino acid;:: = gene dispuption by insertion sequence; del = deletion; ins insertion; sub = substitution;</p><p>**non-functional (STOP mutation in <i>bla</i><sub>OXA-9</sub> gene)</p><p>Results of susceptibility testing (MICs), the molecular analyses of β-lactamases and porins, the efflux properties (EHT), and the synergism testing (FICIs).</p>