10.1371/journal.pone.0126479.t001 Claudia Stein Claudia Stein Oliwia Makarewicz Oliwia Makarewicz Jürgen A. Bohnert Jürgen A. Bohnert Yvonne Pfeifer Yvonne Pfeifer Miriam Kesselmeier Miriam Kesselmeier Stefan Hagel Stefan Hagel Mathias W. Pletz Mathias W. Pletz Results of susceptibility testing (MICs), the molecular analyses of β-lactamases and porins, the efflux properties (EHT), and the synergism testing (FICIs). Public Library of Science 2015 mic resistance ompK combination antibiotic tigecycline Klebsiella pneumoniae Carbapenemase kpc colistin mortality rates infection strain mechanism Dimensional Checkerboard Synergy Analysis 2015-06-11 03:00:26 Dataset https://plos.figshare.com/articles/dataset/_Results_of_susceptibility_testing_MICs_the_molecular_analyses_of_946_lactamases_and_porins_the_efflux_properties_EHT_and_the_synergism_testing_FICIs_/1446440 <p>The EHT and the FICI values are given as median ± standard deviation. Synergistic FICI values are indicated in bold letters. The FICI values indicated in brackets represent the lowest values for the given combination.</p><p>*Strains were obtained from: NRZ = National Reference Laboratory for multidrug-resistant gram-negative bacteria, Ruhr-University Bochum, Germany, and RKI = Robert-Koch-Institut, Wernigerode, Germany; MEM = meropenem; CST = colistin; TCG = tigecycline; FICI = fractional inhibitory concentration index; EHT = efflux half-time; nm = not measureable; aa = amino acid;:: = gene dispuption by insertion sequence; del = deletion; ins insertion; sub = substitution;</p><p>**non-functional (STOP mutation in <i>bla</i><sub>OXA-9</sub> gene)</p><p>Results of susceptibility testing (MICs), the molecular analyses of β-lactamases and porins, the efflux properties (EHT), and the synergism testing (FICIs).</p>