10.1371/journal.pone.0129265.g001
Cuiping Wang
Cuiping
Wang
Rong Jin
Rong
Jin
Anil Nanda
Anil
Nanda
Jinchuan Yan
Jinchuan
Yan
Guohong Li
Guohong
Li
Platelet PI3Kγ contributes to activated platelets induced intima-media thickening after partial ligation.
Public Library of Science
2015
Platelet activation
PI 3K mice
platelet PI 3K deficiency
ec
platelet PI 3K
Platelet PI 3K Contributes
proinflammatory mediator expression
carotid artery ligation
PI 3K platelets
PI 3K
p 38 MAP Kinase
Severely Reduced Flow Conditions Studies
2015-06-08 02:47:16
Figure
https://plos.figshare.com/articles/figure/_Platelet_PI3K_947_contributes_to_activated_platelets_induced_intima_media_thickening_after_partial_ligation_/1439847
<p>(A) Representative Verhoeff’s elastic stained cross sections (level 3) of left common carotid arteries from WT mice treated with PBS (Vehicle), WT platelets (WT plts), or PI3Kγ<sup>-/-</sup> platelets (PI3Kγ<sup>-/-</sup> plts) (n = 5 per group) at 21 d after partial ligation. (B) Schematic diagram of partial ligation and tissue microtomy. Intima+ media areas (C) were measured at seven section levels (200μm intervals), and their mean values were determined. Data are expressed as mean ± SEM. * <i>P</i><0.05 versus vehicle, # <i>P</i><0.05 versus WT platelet-infused mouse. Light microscope magnification is 10×.</p>