10.1371/journal.pone.0129265.g001 Cuiping Wang Cuiping Wang Rong Jin Rong Jin Anil Nanda Anil Nanda Jinchuan Yan Jinchuan Yan Guohong Li Guohong Li Platelet PI3Kγ contributes to activated platelets induced intima-media thickening after partial ligation. Public Library of Science 2015 Platelet activation PI 3K mice platelet PI 3K deficiency ec platelet PI 3K Platelet PI 3K Contributes proinflammatory mediator expression carotid artery ligation PI 3K platelets PI 3K p 38 MAP Kinase Severely Reduced Flow Conditions Studies 2015-06-08 02:47:16 Figure https://plos.figshare.com/articles/figure/_Platelet_PI3K_947_contributes_to_activated_platelets_induced_intima_media_thickening_after_partial_ligation_/1439847 <p>(A) Representative Verhoeff’s elastic stained cross sections (level 3) of left common carotid arteries from WT mice treated with PBS (Vehicle), WT platelets (WT plts), or PI3Kγ<sup>-/-</sup> platelets (PI3Kγ<sup>-/-</sup> plts) (n = 5 per group) at 21 d after partial ligation. (B) Schematic diagram of partial ligation and tissue microtomy. Intima+ media areas (C) were measured at seven section levels (200μm intervals), and their mean values were determined. Data are expressed as mean ± SEM. * <i>P</i><0.05 versus vehicle, # <i>P</i><0.05 versus WT platelet-infused mouse. Light microscope magnification is 10×.</p>