<i>elt-2</i> regulated genes. Dena H. S. Block Kwame Twumasi-Boateng Hae Sung Kang Jolie A. Carlisle Alexandru Hanganu Ty Yu-Jen Lai Michael Shapira 10.1371/journal.pgen.1005265.g001 https://plos.figshare.com/articles/figure/_elt_2_regulated_genes_/1428050 <p><i>A</i>. <i>microarray analysis</i>. Gene expression profiles for 426 transcripts differentially expressed between <i>elt-2(RNAi)</i> and control-treated wildtype worms, when exposed to <i>P</i>. <i>aeruginosa</i> (PA, 12 hours), compared to <i>E</i>. <i>coli</i> (<i>EC</i>). Left, heatmap of raw values (log<sub>2</sub>(fold change over reference RNA)), with bars highlighting clusters of interest; right, curves depicting median-centered expression profiles; black curves represent the median. <i>B</i>. <i>GATA motif distribution</i>. Measured for the consensus TGATAA in 1000bp upstream sequences of genes of the designated subsets; shown as #motifs/gene/100bp; asterisks mark significant deviations from random distribution (p<10<sup>–8</sup>, χ<sup>2</sup>).</p> 2015-05-27 03:44:27 function elegans larvae elegans GATA transcription factors SKN role atf infection resistance elt elegans immunity survival assays hydrolytic enzymes adult intestine Pseudomonas aeruginosa Infection Adult C terminal differentiation microarray analysis gene