<i>elt-2</i> regulated genes.
Dena H. S. Block
Kwame Twumasi-Boateng
Hae Sung Kang
Jolie A. Carlisle
Alexandru Hanganu
Ty Yu-Jen Lai
Michael Shapira
10.1371/journal.pgen.1005265.g001
https://plos.figshare.com/articles/figure/_elt_2_regulated_genes_/1428050
<p><i>A</i>. <i>microarray analysis</i>. Gene expression profiles for 426 transcripts differentially expressed between <i>elt-2(RNAi)</i> and control-treated wildtype worms, when exposed to <i>P</i>. <i>aeruginosa</i> (PA, 12 hours), compared to <i>E</i>. <i>coli</i> (<i>EC</i>). Left, heatmap of raw values (log<sub>2</sub>(fold change over reference RNA)), with bars highlighting clusters of interest; right, curves depicting median-centered expression profiles; black curves represent the median. <i>B</i>. <i>GATA motif distribution</i>. Measured for the consensus TGATAA in 1000bp upstream sequences of genes of the designated subsets; shown as #motifs/gene/100bp; asterisks mark significant deviations from random distribution (p<10<sup>–8</sup>, χ<sup>2</sup>).</p>
2015-05-27 03:44:27
function
elegans larvae
elegans GATA transcription factors
SKN
role
atf
infection resistance
elt
elegans immunity
survival assays
hydrolytic enzymes
adult intestine
Pseudomonas aeruginosa Infection
Adult C
terminal differentiation
microarray analysis
gene