%0 Figure %A I. Kisiela, Dagmara %A Avagyan, Hovhannes %A Friend, Della %A Jalan, Aachal %A Gupta, Shivani %A Interlandi, Gianluca %A Liu, Yan %A Tchesnokova, Veronika %A B. Rodriguez, Victoria %A Sumida, John P. %A Strong, Roland K. %A Wu, Xue-Ru %A E. Thomas, Wendy %A V. Sokurenko, Evgeni %D 2015 %T Effect of mannose on antibody binding. %U https://plos.figshare.com/articles/figure/_Effect_of_mannose_on_antibody_binding_/1414857 %R 10.1371/journal.ppat.1004857.g002 %2 https://plos.figshare.com/ndownloader/files/2067822 %K binding pocket %K receptor %K fimbrial adhesin FimH %K ligand %K conformation %K inhibition %K coli Attachment proteins %K vaccine target protein %K inhibitor %K antibody %K uropathogenic Escherichia coli %X

Dose-response curves of mAb475 (A) and mAb926 (B) binding to fimbrial FimHwt in the absence and presence of 1% (52 mM) mannose. The EC50 values were calculated for each mAb separately from the fitted curves shown using Prism Graphpad 6 software. Data shown are mean ± SEM (n = 3 independent experiments).

%I PLOS Pathogens