Effect of mannose on antibody binding. Dagmara I. Kisiela Hovhannes Avagyan Della Friend Aachal Jalan Shivani Gupta Gianluca Interlandi Yan Liu Veronika Tchesnokova Victoria B. Rodriguez John P. Sumida Roland K. Strong Xue-Ru Wu Wendy E. Thomas Evgeni V. Sokurenko 10.1371/journal.ppat.1004857.g002 https://plos.figshare.com/articles/figure/_Effect_of_mannose_on_antibody_binding_/1414857 <p>Dose-response curves of mAb475 (A) and mAb926 (B) binding to fimbrial FimH<sup>wt</sup> in the absence and presence of 1% (52 mM) mannose. The EC<sub>50</sub> values were calculated for each mAb separately from the fitted curves shown using Prism Graphpad 6 software. Data shown are mean ± SEM (n = 3 independent experiments).</p> 2015-05-14 02:55:38 binding pocket receptor fimbrial adhesin FimH ligand conformation inhibition coli Attachment proteins vaccine target protein inhibitor antibody uropathogenic Escherichia coli