10.1371/journal.ppat.1004857.g001
Dagmara I. Kisiela
Dagmara
I. Kisiela
Hovhannes Avagyan
Hovhannes
Avagyan
Della Friend
Della
Friend
Aachal Jalan
Aachal
Jalan
Shivani Gupta
Shivani
Gupta
Gianluca Interlandi
Gianluca
Interlandi
Yan Liu
Yan
Liu
Veronika Tchesnokova
Veronika
Tchesnokova
Victoria B. Rodriguez
Victoria
B. Rodriguez
John P. Sumida
John P.
Sumida
Roland K. Strong
Roland K.
Strong
Xue-Ru Wu
Xue-Ru
Wu
Wendy E. Thomas
Wendy
E. Thomas
Evgeni V. Sokurenko
Evgeni
V. Sokurenko
Inhibitory potency of mAb926 and mAb475.
Public Library of Science
2015
binding pocket
receptor
fimbrial adhesin FimH
ligand
conformation
inhibition
coli Attachment proteins
vaccine target protein
inhibitor
antibody
uropathogenic Escherichia coli
2015-05-14 02:55:38
Figure
https://plos.figshare.com/articles/figure/_Inhibitory_potency_of_mAb926_and_mAb475_/1414856
<p>Binding of FimH<sup>wt</sup>-expressing <i>E</i>. <i>coli</i> to surface-immobilized yeast mannan in the presence of different concentrations of anti-FimH antibodies. Data are mean ± SEM (n = 5 independent experiments). The IC<sub>50</sub> values were calculated from the fitted curves shown using Prism GraphPad 6 software. **, <i>P</i> ≤ 0.005 (t-test).</p>