10.1371/journal.pone.0123400.g003 Yan Gao Yan Gao Qiudong Su Qiudong Su Yao Yi Yao Yi Zhiyuan Jia Zhiyuan Jia Hao Wang Hao Wang Xuexin Lu Xuexin Lu Feng Qiu Feng Qiu Shengli Bi Shengli Bi Profiles of HAV-specific IgA production in mucosal immune response to vaccination. Public Library of Science 2015 hepatitis protein vaccine hepatitis E virus hav Candidate Mucosal Vaccine sequence Hepatitis E Virus Structural Proteins ifn E infection orf cpg Enhanced Mucosal Immune Responses Induced odn hev reading frame 2 balb tuftsin group tuftsin aa mucosal candidate vaccine virus protein 1 Th 1 response intranasally vp 2015-04-13 05:01:01 Figure https://plos.figshare.com/articles/figure/_Profiles_of_HAV_specific_IgA_production_in_mucosal_immune_response_to_vaccination_/1377350 <p>HAV IgA was detected by indirect ELISA in (A) vaginal secretions, (B) intestine, (C) respiratory tract and (D) stool homogenates of the mouse groups immunized as indicated in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0123400#pone.0123400.g002" target="_blank">Fig 2</a>. Each serum effective dose (presented as the GMT) is the reciprocal value of the maximum positive dilution. Error bars represent the SEM. *, <i>P</i><0.05, **, <i>P</i><0.01, ***, <i>P</i><0.001; ns, no significant difference.</p>