SPR analysis of the interaction of adenine nucleotides to immobilized. <i>M</i>.<i>leprae</i> HSP18 interactions.
Sandip Kumar Nandi
Ayon Chakraborty
Alok Kumar Panda
Sougata Sinha Ray
Rajiv Kumar Kar
Anirban Bhunia
Ashis Biswas
10.1371/journal.pntd.0003661.g002
https://plos.figshare.com/articles/figure/_SPR_analysis_of_the_interaction_of_adenine_nucleotides_to_immobilized_M_leprae_HSP18_interactions_/1357686
<p>Sensorgrams (solid line) of the binding of <b>(A)</b> ATP (0.1–5 μM); <b>(B)</b> ATP-γS (0.1–1 μM); <b>(C)</b> ADP (0.1–100 μM) and <b>(D)</b> AMP (0.1–100 μM) to <i>M</i>. <i>leprae</i> HSP18 covalently captured on a sensor chip at 25°C.</p>
2015-03-26 04:46:04
antigenic proteins act
chaperone function
heat shock protein
Comparative sequence alignment
Small Heat Shock Protein
HSP 18
Molecular docking studies
Mycobacterium leprae bacilli
sequence 49 KADSLDIDIE 58
leprae HSP 18
18 kDa antigen
ATP triggers exposure
leprae HSP 18. ATP perturbs
surface plasmon resonance measurement