Expression of PSMC3IP and EPSTI1 in normal and breast cancer cell lines. Eva Capdevila-Busquets Nahuai Badiola Rodrigo Arroyo Víctor Alcalde Montserrat Soler-López Patrick Aloy 10.1371/journal.pone.0115352.g001 https://plos.figshare.com/articles/figure/_Expression_of_PSMC3IP_and_EPSTI1_in_normal_and_breast_cancer_cell_lines_/1290020 <p>We inspected the endogenous expression of PSMC3IP <b>(A)</b> and EPSTI1 <b>(B)</b> in two types of breast cancer cell lines, MDA-MB-231 and MCF-7, as compared to a normal breast epithelial cell line, MCF-10A. Estimated protein levels based on densitometry (right) of the immunoblots (left) show a PSMC3IP 19- and 15-fold expression in MDA-MB-231 and MCF-7 cells, while EPSTI1 only shows 1.9- and 1.3-fold in each cell line, respectively. Protein levels were normalized based on the loading control protein β-actin. (*<i>P</i> <0.05, **P<0.01, ***<i>P</i> <0.001 vs MCF-10A cells).</p> 2015-01-15 02:47:25 breast cancer cell lines proteasome 26 S subunit ATPase 3 EPSTI 1 Play PSMC 3IP role breast cancer interaction EPSTI 1 gene expression modulation extrinsic apoptotic pathway Breast Cancer Genes PSMC 3IP