10.1371/journal.pone.0116003.g004 Anton A. Nizhnikov Anton A. Nizhnikov Alexander I. Alexandrov Alexander I. Alexandrov Tatyana A. Ryzhova Tatyana A. Ryzhova Olga V. Mitkevich Olga V. Mitkevich Alexander A. Dergalev Alexander A. Dergalev Michael D. Ter-Avanesyan Michael D. Ter-Avanesyan Alexey P. Galkin Alexey P. Galkin 2D-DIGE image of proteins of sarkosyl-insoluble aggregates isolated from the GT81-1C [<i>PSI</i><sup>+</sup>][<i>PIN</i><sup>+</sup>] strain and its [<i>psi</i><sup>−</sup>][<i>pin</i><sup>−</sup>] derivative (A). Public Library of Science 2014 amyloid proteins amyloid aggregates proteomic approach polyglutamine domain protein fractions yeast prions 2 D difference gel electrophoresis sds Sedimented proteins amyloid formation yeast proteins yeast model Proteomic Screening 2014-12-30 03:06:06 Figure https://plos.figshare.com/articles/figure/_2D_DIGE_image_of_proteins_of_sarkosyl_insoluble_aggregates_isolated_from_the_GT81_1C_PSI_PIN_strain_and_its_psi_8722_pin_8722_derivative_A_/1281725 <p>Spots corresponding to proteins from [<i>PSI</i><sup>+</sup>][<i>PIN</i><sup>+</sup>] lysate and the [<i>psi<sup>−</sup></i>][<i>pin</i><sup>−</sup>] control are red and green, respectively, while yellow spots correspond to proteins present in both compared samples. SDS-PAGE image of proteins from the same DRAFs that were insoluble in UTC buffer (B). Proteins identified by mass-spectrometry are indicated. Mr – protein molecular mass markers. Identification data are presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116003#pone-0116003-t004" target="_blank">Table 4</a>; mass spectra are shown in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116003#pone.0116003.s004" target="_blank">S4 Table</a>.</p>