10.1371/journal.pone.0116003.g002
Anton A. Nizhnikov
Anton
A. Nizhnikov
Alexander I. Alexandrov
Alexander
I. Alexandrov
Tatyana A. Ryzhova
Tatyana
A. Ryzhova
Olga V. Mitkevich
Olga
V. Mitkevich
Alexander A. Dergalev
Alexander
A. Dergalev
Michael D. Ter-Avanesyan
Michael
D. Ter-Avanesyan
Alexey P. Galkin
Alexey
P. Galkin
2D-DIGE image of proteins of SDS- (A) or sarkosyl-insoluble (B) aggregates isolated from the BY4742 [<i>PIN</i><sup>+</sup>] strain expressing Aβ-GFP and from its [<i>pin</i><sup>−</sup>] derivative expressing non-fused GFP.
Public Library of Science
2014
amyloid proteins
amyloid aggregates
proteomic approach
polyglutamine domain
protein fractions
yeast prions
2 D difference gel electrophoresis
sds
Sedimented proteins
amyloid formation
yeast proteins
yeast model
Proteomic Screening
2014-12-30 03:06:06
Figure
https://plos.figshare.com/articles/figure/_2D_DIGE_image_of_proteins_of_SDS_A_or_sarkosyl_insoluble_B_aggregates_isolated_from_the_BY4742_PIN_strain_expressing_A_946_GFP_and_from_its_pin_8722_derivative_expressing_non_fused_GFP_/1281721
<p>Spots corresponding to proteins from [<i>PIN</i><sup>+</sup>] cells expressing Aβ-GFP are red, while proteins from GFP-containing cells (control) are green. Yellow spots correspond to proteins present in both compared samples. Proteins identified by mass-spectrometry are indicated. Identification data are presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116003#pone-0116003-t001" target="_blank">Table 1</a> (SDS-insoluble aggregates) and 2 and 3(sarkosyl-insoluble aggregates). Mass-spectra of identified proteins are listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116003#pone.0116003.s001" target="_blank">S1</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116003#pone.0116003.s003" target="_blank">S3 Tables</a>, correspondingly.</p>