10.1371/journal.pone.0116003.g002 Anton A. Nizhnikov Anton A. Nizhnikov Alexander I. Alexandrov Alexander I. Alexandrov Tatyana A. Ryzhova Tatyana A. Ryzhova Olga V. Mitkevich Olga V. Mitkevich Alexander A. Dergalev Alexander A. Dergalev Michael D. Ter-Avanesyan Michael D. Ter-Avanesyan Alexey P. Galkin Alexey P. Galkin 2D-DIGE image of proteins of SDS- (A) or sarkosyl-insoluble (B) aggregates isolated from the BY4742 [<i>PIN</i><sup>+</sup>] strain expressing Aβ-GFP and from its [<i>pin</i><sup>−</sup>] derivative expressing non-fused GFP. Public Library of Science 2014 amyloid proteins amyloid aggregates proteomic approach polyglutamine domain protein fractions yeast prions 2 D difference gel electrophoresis sds Sedimented proteins amyloid formation yeast proteins yeast model Proteomic Screening 2014-12-30 03:06:06 Figure https://plos.figshare.com/articles/figure/_2D_DIGE_image_of_proteins_of_SDS_A_or_sarkosyl_insoluble_B_aggregates_isolated_from_the_BY4742_PIN_strain_expressing_A_946_GFP_and_from_its_pin_8722_derivative_expressing_non_fused_GFP_/1281721 <p>Spots corresponding to proteins from [<i>PIN</i><sup>+</sup>] cells expressing Aβ-GFP are red, while proteins from GFP-containing cells (control) are green. Yellow spots correspond to proteins present in both compared samples. Proteins identified by mass-spectrometry are indicated. Identification data are presented in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116003#pone-0116003-t001" target="_blank">Table 1</a> (SDS-insoluble aggregates) and 2 and 3(sarkosyl-insoluble aggregates). Mass-spectra of identified proteins are listed in <a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116003#pone.0116003.s001" target="_blank">S1</a>–<a href="http://www.plosone.org/article/info:doi/10.1371/journal.pone.0116003#pone.0116003.s003" target="_blank">S3 Tables</a>, correspondingly.</p>