%0 Figure %A Shiraki, Takeru %A Aoyama, Takuma %A Yokoyama, Chiharu %A Hayakawa, Yuka %A Tanaka, Toshiki %A Nishigaki, Kazuhiko %A Sawamura, Tatsuya %A Minatoguchi, Shinya %D 2014 %T Laser Doppler blood flow analysis of WT and LOX-1 KO mice. %U https://plos.figshare.com/articles/figure/_Laser_Doppler_blood_flow_analysis_of_WT_and_LOX_1_KO_mice_/1272397 %R 10.1371/journal.pone.0114542.g001 %2 https://plos.figshare.com/ndownloader/files/1844846 %K p 38 MAPK %K postoperative day 14. Immunohistochemical analysis %K WT mice %K macrophage infiltration %K KO mice show %K cell adhesion molecule %K ROS production assay %K ldl %K LDBF %K hindlimb ischemia model %K right hindlimb ischemia %K nf %K angiogenic factor VEGF %K histological capillary density %K NOX 2 expression %K vcam %K lox %K KO mice %K Western Blot analysis %K hif %K ad %K laser Doppler blood flowmetry %X

A: Representative images of LDBF just before and day 28 after surgery revealed hindlimb blood flow of the ischemic (R: right)/nonischemic (L: left) conditions in a supine position. B: Ischemic/nonischemic hindlimb blood flow ratio (mean±SD) were measured before (Pre), and on days 3, 7, 14, 21 and 28 after right femoral artery ligation. Results are expressed as the ratio of the ischemic hindlimb to nonischemic limb perfusion. , P<0.05 vs. WT; ★★, P<0.01 vs. WT; #, P<0.01 vs. Pre (before surgery), n = 25.

%I PLOS ONE