Regulated silencing of hStau1 protein in neuroblastoma cells. Joan Peredo Patricia Villacé Juan Ortín Susana de Lucas 10.1371/journal.pone.0113704.g006 https://plos.figshare.com/articles/figure/_Regulated_silencing_of_hStau1_protein_in_neuroblastoma_cells_/1251673 <p>Cultures of neuroblastoma SH-SY5Y cells were transduced with a lentiviral construct able to express, under a doxicyclin inducible promoter, RFP and an shRNA with a hStau1 specific silencer (siStau) or an empty shRNA as a control (Ctrl). (A) Combined phase-contrast and fluorescence images of cells treated (bottom) or untreated (top) with doxicyclin. Bar scale correspond to 10 µm. (B) Cell extracts were obtained from the cultures described above and analysed by Western-blot using antibodies specific for hStau1 or ß-actin.</p> 2014-11-25 03:06:46 Staufen 1 mRNA targets dendritic arborisation Staufen 1. neuroblastoma cells translation repression Staufen 1 complexes neuroblastoma cell differentiation Staufen 1 Motor proteins localised translation Human Staufen 1 Associates intracellular localization Neuronal Cell Differentiation cell fate