10.1371/journal.pone.0113834.g004 Hidetoshi Yamada Hidetoshi Yamada Sayaka Kikuchi Sayaka Kikuchi Tomoki Inui Tomoki Inui Hideyuki Takahashi Hideyuki Takahashi Ken-ichi Kimura Ken-ichi Kimura Gentiolactone suppresses transcriptional activity of NF-κB. Public Library of Science 2014 lps Murine Macrophages BackgroundGentian roots inhibition compound RAW 264.7 cells inos extract mrna gentiolactone expression Gentiana triflora nf mechanism cox tnf gentian roots 2014-11-25 02:44:48 Figure https://plos.figshare.com/articles/figure/_Gentiolactone_suppresses_transcriptional_activity_of_NF_954_B_/1251352 <p>RAW264.7 cells were transfected with reporter plasmids and cultured with LPS (1 µg/mL) and gentiolactone (500 µM). At 12 hours after LPS stimulation, luciferase activity was measured. Plotted values represent the mean value ± SD from five independent cultures. Helenalin was used as a positive control.</p>