10.1371/journal.pone.0113834.g002 Hidetoshi Yamada Hidetoshi Yamada Sayaka Kikuchi Sayaka Kikuchi Tomoki Inui Tomoki Inui Hideyuki Takahashi Hideyuki Takahashi Ken-ichi Kimura Ken-ichi Kimura Gentiolactone and cytotoxicity of gentiolactone. Public Library of Science 2014 lps Murine Macrophages BackgroundGentian roots inhibition compound RAW 264.7 cells inos extract mrna gentiolactone expression Gentiana triflora nf mechanism cox tnf gentian roots 2014-11-25 02:44:48 Figure https://plos.figshare.com/articles/figure/_Gentiolactone_and_cytotoxicity_of_gentiolactone_/1251349 <p>A, Structure of gentiolactone. The molecular formula of gentiolactone is C<sub>10</sub>H<sub>12</sub>O<sub>5</sub> and its monoisotopic mass is 212.068. B, RAW264.7 cells were seeded in 6-well culture plates (1×10<sup>6</sup> cells/well) and cultured with gentiolactone or helenalin for 24 hours. At the end of this period, the number of living cells in each well was counted.</p>