Kang, Yu-Lin Ahson Saleem, Moin Wah Chan, Kwok Yat-Ming Yung, Benjamin Ka-Wai Law, Helen Trehalose diminished cell motility in PAN-treated human podocytes. <p>Podocyte were treated with PAN (30 µg/ml) or/and Trehalose (50 mM) for 12 h. (<b>A</b>) PAN-increased podocyte motility was suppressed by trehalose. The representative images were taken under inverted microscope (50×). (<b>B</b>) The number of cells migrating into the gap was calculated for evaluating podocyte motility. The migrated podocytes after PAN treatment increased significantly, whereas trehalose suppressed this enhanced motility. **<i>p</i><0.01, ***<i>p</i><0.001 versus CON, n = 6.</p> Alleviates Human Podocyte Injury;Puromycin Aminonucleoside Treatment Glomerular diseases;reactive oxygen species involvement;attenuate podocyte injury;Lactate dehydrogenase activity;autophagy;mTOR Independent Autophagy Inducer;Podocyte apoptosis;change nephrotic syndrome;podocyte injury;trehalose;actin cytoskeleton rearrangement;LC 3 puncta 2014-11-20
    https://plos.figshare.com/articles/figure/_Trehalose_diminished_cell_motility_in_PAN_treated_human_podocytes_/1247867
10.1371/journal.pone.0113520.g007